CONSENT OF KESSELMAN & KESSELMAN, A MEMBER FIRM OF PRICEWATERHOUSECOOPERS INTERNATIONAL LIMITED, INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
Published on April 1, 2019
Exhibit 15.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We hereby consent to the incorporation by reference in the Registration Statement on Form F-3 (No. 333-229486) and on Form S-8 (No. 333-229163) of CollPlant Holdings Ltd. of our report dated March 31, 2019 relating to the financial statements, which appears in this Form 20-F.
| Tel-Aviv, Israel | /s/ Kesselman & Kesselman |
| April 1, 2019 | Certified Public Accountants (Isr.) |
| A
member firm of PricewaterhouseCoopers International Limited |
Kesselman & Kesselman, Trade Tower, 25 Hamered Street, Tel-Aviv 6812508, Israel,
P.O Box 50005 Tel-Aviv 6150001 Telephone: +972 -3- 7954555, Fax:+972 -3- 7954556, www.pwc.com/il